Metagenomic testing for your patients.
UCSF offers a clinical test available on cerebrospinal fluid for patients with idiopathic meningitis/encephalitis of unknown etiology. Testing must be ordered by a licensed provider authorized to order clinical laboratory tests and will be reported to the referring laboratory.
Here are the steps to order a test:
- Refer to your lab director to ensure your institution has an established account. See Set Up Account.
- Requisition forms are available with your lab director once you have an account. Consult with your lab director to send your patient sample.
Testing is currently available on cerebrospinal fluid (CSF).
Please send CSF in a sterile tube:
- Minimum volume 1 mL (preferred 2 mL)
- Aliquot (if necessary) only under sterile conditions
- Freeze at -70C (-20C is acceptable) within 5 days of collection (recommended within 24 hours)
For further information, see Lab Manual
Ship CSF on dry ice via overnight delivery together with the requisition form.
Results are available 1-2 weeks after specimen receipt. Reports are faxed to your lab as soon as they are available. Please contact your lab for results.
UCSF Laboratory Medicine providers offer consultations and interpretation of results for tested samples through the Clinical Microbial Sequencing Board. To request a consultation on a tested or pending sample, please fill out the contact form.
CSF containing significant pleocytosis may have reduced sensitivity of detection for DNA viruses, bacteria, fungi, and parasites.
Extended storage at 4°C and multiple freeze-thaw cycles may reduce the ability to detect pathogens, especially for RNA viruses.
Detection of organisms is based on the presence of detectable nucleic acid; some microorganism types that are present transiently or at very low levels may be better diagnosed through antibody testing.